A superb display of late runs from Francesco Bagnaia displayed his rapid pace in MotoGP second practice, putting the Italian on top of the timesheets in his local track of Misano.
Marc Marquez once again finished the session in second place but finished 0.185s adrift of his 2025 factory team-mate.
The Pramac Racing duo of Jorge Martin and Franco Morbidelli finished third and fourth, respectively, with the pair separated by only 0.001 of a second.
Enea Bastianini followed his team-mate Bagnaia into Q2, with rookie Acosta finishing as the clear distant KTM rider aboard his GasGas Tech3 bike.
Marco Bezzecchi formulated a strong seventh spot despite his struggles earlier in the day, with Maverick Vinales finishing in eighth spot. His team-mate Aleix Espargaro endured a late crash in Turn 1 on his final run which put him out of Q2 contention.
Fabio Quartararo cemented his place in Q2, his first since his home race at Le Mans earlier in the year, to deliver a crucial result for the Japanese marque which has spent a monumental amount of time fixing its bad form.
Jack Miller established a strong practice result of tenth spot to force his team-mate Brad Binder into Q1 on Saturday, with the duo separated by a tenth of a second.
Pol Espargaro came close to a Q2 spot but finished the session within 0.001s of his own brother Aleix, with the top 13 riders separated by 0.749s.
Miguel Oliveira could only muster the 14th spot aboard his Trackhouse Aprilia, with Johann Zarco once again finishing as the lead Honda rider.
Fabio Di Giannantonio’s struggling Friday continued with VR46 Ducati, with the Italian finishing 16th.
Alex Rins’ session in 17th with Yamaha, ahead of surprise name Alex Marquez in 18th spot with it all to do for Saturday’s qualifying.
Augusto Fernandez and Takaaki Nakagami occupied 19th and 20th, respectively, ahead of Raul Fernandez, who rounded off a disappointing day for the American outfit Trackhouse.
Luca Marini and Stefan Bradl occupied the final two spots for Honda, with both riders unable to compete with their team-mates.
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