| # | Rider | Bike | Points | |
|---|---|---|---|---|
 | Fabio Quartararo | Yamaha | 172 | |
 | Aleix Espargaro | Aprilia | 151 | |
| Johann Zarco | Ducati | 114 | |
 | Francesco Bagnaia | Ducati | 106 | |
| Enea Bastianini | Ducati | 105 | |
 | Brad Binder | KTM | 93 | |
 | Jack Miller | Ducati | 91 | |
| Joan Mir | Suzuki | 77 | |
| Alex Rins | Suzuki | 75 | |
 | Miguel Oliveira | KTM | 71 | |
| Jorge Martin | Ducati | 70 | |
| Maverick Vinales | Aprilia | 62 | |
| Marc Marquez | Honda | 60 | |
| Marco Bezzecchi | Ducati | 55 | |
| Luca Marini | Ducati | 52 | |
 | Takaaki Nakagami | Honda | 42 | |
| Pol Espargaro | Honda | 40 | |
| Alex Marquez | Honda | 27 | |
| Franco Morbidelli | Yamaha | 25 | |
| Fabio Di Giannantonio | Ducati | 18 | |
| Darryn Binder | Yamaha | 10 | |
| Andrea Dovizioso | Yamaha | 10 | |
| Remy Gardner | KTM | 9 | |
| Raul Fernandez | KTM | 5 |
2022 MotoGP Standings
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